Panama Canal Cruises

Set sail with Princess® – the best Panama Canal cruise line

Best Cruise
Line Itineraries
13-Time Winner
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We’re the number one cruise line sailing to this bucket list destination, and as awe-inspiring as it is to travel through one of Condé Nast Traveller’s 7 Cruise Wonders of the World, we’ll help you explore equally fascinating places along the way. So stretch out on a Caribbean beach, admire the pristine rainforests, stroll the cobbled streets of colonial towns and journey through the fabled Panama Canal with Princess.

Watch Panama Canal cruise video:
Panama Canal video

View cruises From the East Coast Roundtrip Ft. Lauderdale
  • Roundtrip from Ft. Lauderdale
  • Experience a partial transit of the Panama Canal New Locks
  • Visit the pristine beaches of the Caribbean and explore the lush rainforests of Costa Rica
View cruises Ocean to Ocean Between Atlantic and Pacific Oceans
  • Sail from the East Coast to the West Coast or vice versa. Cruise from Ft. Lauderdale to Los Angeles or San Francisco, or cruise from either of those two West Coast cities to Ft. Lauderdale.
  • Ideal itinerary for those who want to experience a full transit of the Panama Canal
  • Transit all three sets of locks
Princess MedallionClass

Princess® MedallionClass®

Explore destinations easily on a MedallionClass vacation. Taking in balcony or top deck views, and don’t want to move? Order drinks that find you. Want to make the most of your time away? Design each perfect day with our interactive activity planner. Hate to wait when boarding or disembarking in port? Choose your preferred arrival window and make gangway reservations. Enjoy more time to connect with the places you sail.

Learn more about Princess MedallionClass | Learn more about MedallionNet® Internet 

2022 - 2023 Panama Canal New Cruise Itineraries. Learn more

Why Princess is the #1 Panama Canal Cruise Line

Meaningful travel to a bucket-list destination
Man leaning over the railing of a ship, holding his camera, viewing the locks of the Panama Canal

The Leader in the Panama Canal Cruise Ports

From ships custom built to sail the massive locks to immersive on-board programs and onshore adventures that inspire, Princess is the number one way to explore this epic phenomenon. We've sailed the Panama Canal since 1967 and we have more itinerary choices and departures of any cruise line in the region.

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Photo: View of locks from the ship

A woman dressed in colourful, native attire balancing a bowl of fruit on her head

Destination Immersion

We craft our Panama Canal itineraries to enrich our guests' experiences to provide the most exposure to this bucket-list destination. You'll be enchanted by Spanish and Dutch cities dating back centuries, as well as diverse tropical rainforests, white-sand beaches, dramatic volcanoes and UNESCO World Heritage Sites. And Princess provides live narration from the bridge while transiting the locks, just one reason we were voted "Best Cruise Line for Enrichment" by Cruise International.

Learn more about Panama Canal cruise ports

Photo: Las Bovedas in Cartagena, Colombia

Image of the Princess Cruises Carnaval de Panama Festival of the World celebration

Panama Canal Cruise On-board Experience

Princess brings the Panama Canal and surrounding regions to life on-board. Our Carnaval de Panama Festival of the World celebration focuses on indigenous music and dance, locally inspired cuisine, plus expert guest speakers and enrichment programs that put the spotlight on the unique history of the Canal.

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Photo: Carnaval de Panama

2 people riding colourful bikes on a small street next to colourful houses covered with flowers cascading from the rooftops

Abundant Adventures Ashore

Each voyage offers myriad experiences and cultures. There is something for every type of explorer in this culturally diverse region. Choose from immersive excursions such as exploring the engineering mastery of the Canal, trekking through surrounding rainforests, visiting local villages and relaxing on the pristine beaches of the Caribbean.

Learn more about Panama Canal cruise excursions

Photo: Old City in Cartagena, Colombia

Let Princess Get You There

Embrace Panama's rich history and culture
A nighttime view of the Long Beach skyline

Cruise Plus Hotel Packages

Add peace of mind and a sense of security to your holiday with a Cruise Plus® Hotel Package. Give yourself a few days to relax either before or after your Panama Canal cruise and take in the sights of a sensational city. Princess handles all the details – including transfers and luggage handling – with accommodations selected for their incredible locations and excellent service.

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